About
Tony Natale, M.D. blends his extensive business, investment and company formation experience with a background in clinical medicine. Dr. Natale has invested across a number of therapeutic areas, including orthopedics, ENT, ophthalmology, GI, minimally invasive technologies, robotics and women’s health. A committed board member, Dr. Natale works alongside entrepreneurs to build out management teams, establish effective corporate governance and bring operational discipline to R&D and early commercialization efforts. Dr. Natale was previously with Prism Ventures and MDS Capital where he made and managed investments in the medical technology sector. He has been a founder, director and/or lead investor of several venture-backed life sciences companies, including Mako Surgical. Dr. Natale trained in General Surgery and Otolaryngology/Head and Neck Surgery at the University of Connecticut and Hartford Hospital and held clinical appointments in Hartford area hospitals before transitioning into
Position in the VCSift Database
- • 3 investors at Prism Venture Management are tracked.
- • 3 investors hold the Venture Partner role in VCSift. Anthony Natale is one of them.
Data sourced from 410,343 investor profiles. Updated June 2026.
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