SI

Sam Isaly

Founder at Exome Asset Management

New York, US

About

Samuel D. Isaly is Managing Partner and Founder of Exome Asset Management. Sam Isaly is an experienced healthcare fund manager and has been active in global healthcare investing and analysis for over 45 years. Over the course of his career, Sam has been a pharmaceutical analyst with Chase Manhattan Bank, Merrill Lynch, Legg Mason, and S.G. Warburg. In 1989, Sam launched OrbiMed Advisors LLC. During his time at OrbiMed, Sam was the portfolio manager of Worldwide Healthcare Trust Plc for 22 years. Sam received an A.B. in Economics from Princeton University and a M.Sc. (Economics) from The London School of Economics.

Position in the VCSift Database

  • 3 investors at Exome Asset Management are tracked.
  • 2,490 investors hold the Founder role in VCSift. Sam Isaly is one of them.
  • 10,621 investors are based in New York, New York, United States.

Data sourced from 410,343 investor profiles. Updated June 2026.

Investment Focus

Contact Information

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